Infertility affects at least 10 percent of the population, according to Resolve, the National Infertility Association.
This week is Infertility Awareness Week and social media pages are full of stories both heartbreaking and inspiring.
Jenni Moore, of Reidsville, and her husband wanted to have a baby for years and for some reason couldn't; their infertility is still unexplained.
They went through pills, shots, IVF treatments and two devastating miscarriages. "We grieved that loss, we did a lot of thinking. And we decided that our main goal was to be parents. It wasn't to be pregnant -- it was to be parents. So we decided to adopt."
Adoption was its own roller coaster, Jenni pointed out, but they now have a precious 1-year-old daughter.
"Every heartbreak, every tear, every dollar, every single second of it has been worth it. The second I laid my eyes on her!" Jenni insisted.
Her goal in sharing her story -- and promoting Infertility Awareness Week -- is twofold.
First, she hopes to remind people to be sensitive about asking personal questions. "When you have family members and friends who don't have kids, don't say, 'Well when are you going to have a baby? What's taking you so long?' Because you don't know how hurtful that question could be," she pointed out.
Second, she wants other women and men to know they are not alone.
That's the same message Registered Nurse and IVF Coordinator Lori Marion has.
"There's definitely help. You're not alone. It's something that is scary to reach out and ask for that help- but once you do you're going to find you've got lots of support and lots of options out there to achieve the dream of having a family."
Marion works with Dr. Tamer Yalcinkaya at Carolinas Fertility Institute in Winston-Salem.
"We would say that half the people may be infertile may come from the male component, the other half is the female component. But on average 10 percent of couples go through some form of infertility," she added.
She said typical medical options to help with infertility include medications, artificial insemination, or In Vitro Fertilization (IVF).
Other folks may decide to adopt a child or choose not to have children.
Jenni and her friend, Katy Gregg, started an infertility support group in the Reidsville area.
Cone Health offers a support group too, with new sessions starting May 11.
Wake Forest Health has a Center for Reproductive Health with several Piedmont locations.