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Baltimore Orioles game on Wednesday to be played without fans

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An empty Oriole Park at Camden Yards is shown after the game between the Baltimore Orioles and the Chicago White Sox was postponed on April 27, 2015 in Baltimore, Maryland. The move comes amid violent clashes between police and youths, according to news reports, the aftermath of the death of Freddie Gray on April 19 after suffering a fatal spinal injury while in police custody. (Greg Fiume/Getty Images)

An empty Oriole Park at Camden Yards is shown after the game between the Baltimore Orioles and the Chicago White Sox was postponed on April 27, 2015 in Baltimore, Maryland. The move comes amid violent clashes between police and youths, according to news reports, the aftermath of the death of Freddie Gray on April 19 after suffering a fatal spinal injury while in police custody. (Greg Fiume/Getty Images)

BALTIMORE — Wednesday’s game between the Baltimore Orioles and Chicago White Sox will be closed to the public, the Orioles announced Tuesday.

The closed-door contest follows the postponements of Monday’s and Tuesday’s games against the White Sox until May 28 following unrest in Baltimore.

“After conferring with local officials, it was determined that Wednesday afternoon’s game should be played without fan admittance in order to minimize safety concerns,” Major League Baseball said in a statement.

The game at Oriole Park at Camden Yards is scheduled to begin at 2 p.m. ET Wednesday.

The office of new Commissioner Rob Manfred said the league and Orioles will keep an eye on the situation in Baltimore.

“Our thoughts are with all those who have been affected by violence in Baltimore, and everyone in our game hopes for peace and the safety of a great American city,” Manfred said.

A source within MLB told CNN the league is not aware of any prior closed-door games in major league history.

The game changes come as the situation in the city remains tense following Monday’s riots — with more protests and arrests Tuesday.